Topic
Mass spectrometry research, explained
5 open-access mass spectrometry studies, each with a flashcard deck and a quiz.
- Screening reactions in one-second DESI-MS droplets
Desorption electrospray ionization mass spectrometry reads amine alkylation and Suzuki hits from nanoliter spots in about a second.
- Native nano-DESI images intact kidney proteins
Ammonium-acetate nano-DESI mass spectrometry imaging maps folded proteins and a noncovalent S100-A6 dimer in rat kidney at finer spatial scale than LESA.
- MS sequence maps of mRNA using partial RNase T1
A short digest with bead-bound RNase T1 plus tandem MS covers more than 80% of long mRNA sequences in one run, beating complete T1 maps.
- LC-MS/MS assay and microsomal half-life of pemigatinib
A two-minute LC-MS/MS method quantifies pemigatinib in human liver microsomes and finds a 27.29 min half-life and moderate CLint.
- He tagging maps copper cluster ion shapes
Helium nanodroplet mass spectrometry of 63Cu clusters shows magic He shells that match computed binding sites, including twisted-X Cu5+.