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Woebot chatbot for substance use

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An 8-week fully automated Woebot SUD program showed pre–post drops in substance use, cravings, depression, and anxiety in a single-group study.

Source

A Therapeutic Relational Agent for Reducing Problematic Substance Use (Woebot): Development and Usability Study

Prochaska JJ, Vogel EA, Chieng A, et al. · Journal of medical Internet research · 2021

doi.org/10.2196/24850Read the full paper ↗117 citationscc by

Study at a glance

Design
Human experiment — Single-group 8-week pre–post usability/feasibility evaluation (no control)
N
N=101 · 101 enrolled; 51 completed the post-treatment survey
Population
Adults initiating a therapeutic chatbot for problematic substance use
Outcome
Past-month use occasions, AUDIT-C/DAST-10, cravings, PHQ-8, GAD-7 over 8 weeks

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Woebot chatbot for substance use

These passages occur verbatim in the stored paper text. They support the points listed below; they do not verify every statement in the explanation.

101 participants formed the analytic sample

The analytic sample consisted of 101 participants who ultimately registered with W-SUDs and initiated use.

48.5% reported lifetime GAD

Most (73/101, 72.3%) reported a lifetime psychiatric diagnosis, most commonly generalized anxiety disorder (49/101, 48.5%) and unipolar depression (45/101, 44.6%), with 47.5% (48/101) reporting multiple lifetime psychiatric diagnoses; few (6/101, 5.9%) reported a SUD diagnosis, 43.6% (44/101) were currently taking psychiatric medication, and 25.7% (26/101) were currently in therapy.
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What they did

101 adults who started Woebot for substance use (W-SUDs) completed an 8-week single-group pre–post evaluation of use occasions, AUDIT-C/DAST-10, cravings, confidence, PHQ-8, GAD-7, and pain.

What they found

Past-month use occasions, AUDIT-C, DAST-10, PHQ-8, and GAD-7 improved (all P<.05). In-app craving ratings fell roughly by half by weeks 8–9. Engagement averaged about 15.7 use days over 8 weeks. Authors call the approach feasible and acceptable but note the need for controlled efficacy trials.

The limits

What it doesn't show

Without a control group, pandemic-era substance-use shifts and regression to the mean can explain change. Few participants had diagnosed SUD, and posttreatment completers were a subset of enrollees.

Key terms

Woebot / W-SUDs
Text conversational agent adapted for substance-use treatment.
Conversational agent
Automated chatbot delivering therapeutic check-ins and skills.
AUDIT-C
Brief alcohol screening/severity measure.
DAST-10
Drug Abuse Screening Test score for drug-use problems.
PHQ-8
Eight-item depression symptom scale used here.
Single-group pre–post design
Everyone receives the intervention; change is within-person over time.

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What delivery modality was tested?

Common questions

How many started W-SUDs?

Analytic sample of 101 participants.

What mood scales were used?

PHQ-8 for depression and GAD-7 for anxiety.

Did cravings change?

Yes—ratings were about half of week-1 levels by weeks 8–9.

Was there a control arm?

No; it was a single-group pre–post study.

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