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Phthalates in Egyptian premenstrual girls

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Egyptian girls had much less MBzP than US girls but several-fold more MiBP, especially with plastic food storage.

Source

Exposure to phthalates among premenstrual girls from rural and urban Gharbiah, Egypt: a pilot exposure assessment study

Colacino JA, Soliman AS, Calafat AM, et al. · Environmental health : a global access science source · 2011

doi.org/10.1186/1476-069x-10-40Read the full paper ↗27 citationscc by

Study at a glance

Design
Cross-sectional — Pilot urinary phthalate comparison of rural vs urban Egyptian girls and NHANES matches
N
N=60 · 30 urban and 30 rural premenstrual girls (mean age 11.5)
Population
Premenstrual girls in Gharbiah, Egypt
Outcome
Urinary phthalate metabolites (MEP, MiBP, MBzP) by urbanicity and food-storage practices

Structured fields used in claim comparison tables when every cited study has a complete layer.

What they did

Measured urinary phthalate metabolites in 30 urban and 30 rural premenstrual girls from Gharbiah, Egypt, and compared them with matched NHANES girls.

What they found

MEP was highest (urban median 98.8 ng/mL); SG-adjusted MBzP, MCPP, and MiBP were higher in urban girls; MiBP rose with plastic storage and canned food; US MBzP medians were far higher.

The limits

What it doesn't show

Small sample cannot explain urban–rural breast-cancer differences by phthalates alone.

Key terms

Phthalate
Plasticizer chemical; metabolites measured in urine.
MEP
Monoethyl phthalate, from diethyl phthalate.
MiBP
Mono-isobutyl phthalate, from DiBP.
MBzP
Monobenzyl phthalate, from benzyl butyl phthalate.
DEHP
Di-(2-ethylhexyl) phthalate used in flexible PVC.
Specific gravity
Urine-dilution adjustment metric.

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Urban and rural n:

Common questions

Sample?

30 urban and 30 rural girls.

Mean age?

11.5 years.

Highest metabolite?

MEP.

Urban MEP median?

98.8 ng/mL.

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