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ITO electrodes are active everywhere at 50 nm

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Thousands of nanoscale voltammograms show every ITO patch oxidizes ferrocenedimethanol; only 0.2% is fully reversible, and the old sparse-site model fails.

Source

Nanoscale Visualization of Electrochemical Activity at Indium Tin Oxide Electrodes

Wahab OJ, Kang M, Meloni GN, et al. · Analytical chemistry · 2022

doi.org/10.1021/acs.analchem.1c05168Read the full paper ↗24 citationscc by

Study at a glance

Design
Other — SECCM nanoscale LSV mapping of ITO with Butler–Volmer kinetic fitting
N
Thousands of landing sites on ITO — surface mapping, not a cohort N
Population
Indium tin oxide electrode surfaces
Outcome
Spatial distribution of heterogeneous electron-transfer rate constants

Structured fields used in claim comparison tables when every cited study has a complete layer.

What they did

Authors scanned ITO with a 50 nm SECCM nanopipette, recording FcDM0/+ LSVs at thousands of landings, then fit k0 and α with finite-element Butler–Volmer models and compared the map with macroscale CV.

What they found

The entire surface is active at ~50 nm resolution. 0.2% of area is reversible (k0 ≥ 1 cm s−1); 85.2% has mean k0 = 4.2×10−2 cm s−1; 14.6% is much slower (8×10−4 cm s−1). Weighted average k0 ≈ 3.61×10−2 cm s−1. Macroscopic “blocked electrode” interpretations overstate inert area; film resistance likely dominates macro kinetics.

The limits

What it doesn't show

The study uses one high-conductivity ITO grade and one outer-sphere couple; inner-sphere electrocatalysis maps are not reported.

Key terms

SECCM
Scanning electrochemical cell microscopy with a meniscus nanopipette cell.
ITO
Indium tin oxide, a transparent conducting oxide electrode.
FcDM
1,1′-Ferrocenedimethanol, a fast outer-sphere redox probe.
k0
Standard heterogeneous electron-transfer rate constant.
Blocked-electrode model
Macro interpretation that only sparse 50–200 nm sites are active—rejected here.

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Quiz yourself

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At 50 nm resolution ITO is:

Common questions

Is most of ITO inert?

No—the whole surface is active at 50 nm resolution.

How much is fully reversible?

About 0.2% of the area.

Typical k0?

Most sites ~4.2×10−2 cm s−1; average 3.61×10−2.

Why did macro CV look worse?

Likely lateral film resistance, not dead patches.

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