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Randomized trials

Interdisciplinary frailty RCT

Cameron ID, Fairhall N, Langron C, et al. · BMC medicine · 2013

Open access · cc by · source: Europe PMC

A 12-month multifactorial interdisciplinary program reduced frailty prevalence and improved mobility versus usual care in frail older adults in Sydney.

Study at a glance

Design
RCT — Single-center RCT; year-long multifactorial interdisciplinary intervention vs usual care
N
N=241 · Enrolled of 322 eligible (75%)
Population
Frail older adults in an Australian health system (mean age ~83)
Outcome
Frailty prevalence and SPPB mobility at 3 and 12 months

Structured fields used in claim comparison tables when every cited study has a complete layer.

Key findings

At 12 months, frailty prevalence was 14.7 percentage points lower with intervention (NNT ≈ 6.8) and SPPB mobility improved relative to controls; effects were clearer at 12 months than at 3 months.

Methodology

A single-center RCT randomized frail older adults to a year-long multifactorial interdisciplinary intervention (physiotherapy, nutrition, medical review as needed) or usual care, assessing frailty and SPPB at 3 and 12 months.

Limitations

Results are from one Australian health system and do not isolate which component drove benefit or guarantee mortality reduction.

How this study connects

Role on claims

Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.

  • SupportsRandomized Trialsconcept

    Multiple studies in this library examine randomized trials with empirical patient or population outcomes rather than opinion alone.

    Evidence for the claim as stated.

  • SupportsRandomized Trialsconcept

    At 12 months, frailty prevalence was 14.7 percentage points lower with intervention (NNT ≈ 6.8) and SPPB mobility improved relative to controls; effects were clearer at 12 months than at 3 months.

    Evidence for the claim as stated.

  • SupportsRandomized Trialsconcept

    Effect sizes and settings differ across randomized trials studies — digital vs clinic, trial vs observational — so results should not be pooled casually.

    Evidence for the claim as stated.

Open questions

Tensions this paper is part of

From concept pages' “where studies disagree.” Disagreement means the same question; scope means different assays, populations, or outcomes.

Related papers in this topic

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