developmental-coordination
Do kids with DCD have different cerebellar structure?
Open access · cc by · source: Europe PMC
In 46 children (34 DCD, 12 TD), VBM found reduced grey matter in brainstem and several cerebellar lobules, and lower volumes tracked worse MABC-2 motor scores.
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Do kids with DCD have different cerebellar structure?
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46 children were scanned (12 TD, 34 DCD).
Forty-six children (12 typically-developing and 34 with DCD) were investigated using high resolution T1-weighted images, which were then processed using the spatially unbiased atlas template of the cerebellum and brainstem (SUIT) toolbox for a region of interest-based examination of the cerebellum.
DCD affects ~450,000 Canadian children.
Developmental Coordination Disorder (DCD) is a neurodevelopmental disorder that affects ∼450,000 Canadian children, or roughly 1-to-2 children in every classroom ( American Psychiatric Association, 2013 ; Statistics Canada, 2020 ).
Key findings
DCD showed reduced grey matter in brainstem, crus I (bilateral), right crus II, left VI, right VIIb, and right VIIIa. Positive correlations linked higher MABC-2 percentiles with greater volume in brainstem, left crus I, right VIIb, and right VIIIa.
Methodology
Acquired high-resolution T1 scans in 8–12-year-olds and analysed cerebellum/brainstem with the SUIT toolbox, then correlated regional volumes with Movement Assessment Battery for Children-2 scores.
Limitations
Cross-sectional morphometry cannot prove that volume loss causes DCD; unequal group sizes and comorbidity (e.g., ADHD symptoms) limit causal inference.
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