developmental-coordination
Do kids with DCD have different cerebellar structure?
Open access · cc by · source: Europe PMC
In 46 children (34 DCD, 12 TD), VBM found reduced grey matter in brainstem and several cerebellar lobules, and lower volumes tracked worse MABC-2 motor scores.
Key findings
DCD showed reduced grey matter in brainstem, crus I (bilateral), right crus II, left VI, right VIIb, and right VIIIa. Positive correlations linked higher MABC-2 percentiles with greater volume in brainstem, left crus I, right VIIb, and right VIIIa.
Methodology
Acquired high-resolution T1 scans in 8–12-year-olds and analysed cerebellum/brainstem with the SUIT toolbox, then correlated regional volumes with Movement Assessment Battery for Children-2 scores.
Limitations
Cross-sectional morphometry cannot prove that volume loss causes DCD; unequal group sizes and comorbidity (e.g., ADHD symptoms) limit causal inference.
How this study connects
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