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Reaction mechanisms

Ultrasound microdroplets make H2O2 from dissolved O2

Zhou X, Du S, Zhang W, et al. · Chemical science · 2025

Open access · cc by · source: Europe PMC

Water-in-hexadecane droplets under 40 kHz ultrasound produce H2O2 at 0.24 mM min−1, almost entirely at the oil–water interface via superoxide from dissolved oxygen.

Key findings

H2O2 reaches 14.37 mM in 1 h (0.24 mM min−1); ~99% forms at the interface. Superoxide is ~10× H2O2 and ~1000× ·OH. 18O shows peroxide oxygen comes from O2, not water.

Methodology

Authors emulsified water in hexadecane with an ultrasonic bath, quantified H2O2 versus time, blocked the interface with surfactant, purged O2, used 18O2/H218O mass spectrometry, and compared NBT superoxide versus TA hydroxyl yields.

Limitations

The mechanism is for ultrasound-driven water-in-oil droplets, not spontaneous H2O2 in sprayed air–water microdroplets without ultrasound.

How this study connects

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