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Diabetes

Can kitchen curcumin help lipid and diabetes pathways via ROS?

Cheng M, Ding F, Li L, et al. · Frontiers in pharmacology · 2025

Open access · cc by · source: Europe PMC

This review argues curcumin eases lipid-metabolism diseases mainly by dialing down oxidative stress.

Study at a glance

Design
Other — Narrative literature review (PubMed/Web of Science; focus 2014–2024) of curcumin vs oxidative stress in lipid-metabolism diseases
N
No primary analytic N; synthesized in vivo, in vitro, and clinical literature rather than a new cohort
Population
Published experimental and clinical studies of curcumin in lipid-metabolism–related diseases
Outcome
Mechanistic synthesis of curcumin’s antioxidant effects across hyperlipidemia, NAFLD, atherosclerosis, obesity, and diabetes

Structured fields used in claim comparison tables when every cited study has a complete layer.

Key findings

They frame oxidative stress and lipid disorders as a vicious cycle and position curcumin’s antioxidant/anti-inflammatory actions as reducing ROS, lowering fat deposition, increasing fatty acid uptake, and improving insulin sensitivity across those disease areas.

Methodology

Authors searched PubMed and Web of Science (mainly 2014–2024) on curcumin/turmeric, oxidative stress, and lipid disorders, then synthesized experimental and clinical evidence across hyperlipidemia, NAFLD, atherosclerosis, obesity, and diabetes, including bioavailability strategies.

Limitations

It is not a new trial quantifying clinical benefit, dose, or formulation; bioavailability and study heterogeneity still limit direct prescribing claims.

How this study connects

Role on claims

Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.

Not yet placed on a claim. This paper has study layers, but no concept page yet cites it as support, challenge, or qualifier.

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