Functional connectivity
Which brain circuits control the bladder?
Open access · cc by · source: Europe PMC
This review maps bladder-control regions/networks and notes only six micturition-phase imaging studies, with LPFC/pons most often activated while voiding.
How this study connects
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Study at a glance
- Design
- Other — Narrative review of functional imaging and brain-network models of bladder control
- N
- N=6 · Highlights six prior micturition-phase imaging studies (vs more storage-phase work)
- Population
- Healthy subjects and patients with bladder-control disorders in reviewed imaging studies
- Outcome
- Synthesis of regions/networks for storage vs micturition and disease-related FC changes
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Inspect source passages
Which brain circuits control the bladder?
These passages occur verbatim in the stored paper text. They support the points listed below; they do not verify every statement in the explanation.
Only six prior micturition-phase imaging studies.
Only six previous brain functional imaging studies on the micturition phase have been conducted, far fewer than those on the storage phase.
LPFC/IFG and pons activated five times more often in tally.
the frequency of activation of brain regions during micturition was five times more for the LPFC/inferior frontal gyrus and pons
Key findings
Many regions from pons/PAG to prefrontal/insula participate via networks; LPFC active in storage and voiding, MPFC flips, pons mainly in micturition; extends Griffiths network model.
Methodology
Reviewed functional imaging/FC literature (and authors’ findings) across storage/micturition and disorders such as OAB and IC/BPS.
Limitations
Review synthesis is not a new single-cohort experiment proving one causal circuit.
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