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Pharmacology

Which Indian traditional medicines are being eyed for COVID-19?

Ahmad S, Zahiruddin S, Parveen B, et al. · Frontiers in pharmacology · 2020

Open access · cc by · source: Europe PMC

This review prioritizes AYUSH formulations and Indian plants with antiviral, immunomodulatory, and anti-inflammatory records for COVID-19 testing amid India’s then-<1.5% case fatality narrative.

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Which Indian traditional medicines are being eyed for COVID-19?

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India case fatality rate cited below 1.50%.

case fatality rate is below 1.50%

More than 50% of discussed trials sponsored by government/AYUSH stakeholders.

More than 50% of these trials were sponsored by the government and various stakeholders associated with the Ministry of AYUSH
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Key findings

Authors argue routine immunomodulator plant/AYUSH use may relate to India’s relatively lower reported fatality, highlight immunity-enhancing/anti-inflammatory/antiviral herbal evidence, note >50% of related trials linked to Ministry of AYUSH stakeholders, and urge priority preclinical/clinical testing of promising leads.

Methodology

Reviewed AYUSH-recommended formulations/ingredients, commonly used Indian medicinal plants, and plants with antiviral/immunomodulatory/anti-allergic–anti-inflammatory reports, categorizing them for research prioritization and summarizing ongoing AYUSH clinical-trial activity.

Limitations

Not an RCT proving any named herb cures COVID-19; causal claims about national fatality rates are speculative.

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