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Photochemistry

Platinum photoredox catalysts for trifluoromethylation

Choi WJ, Choi S, Ohkubo K, et al. · Chemical science · 2015

Open access · cc by · source: Europe PMC

Cyclometalated Pt(II) complexes trifluoromethylate unactivated alkenes in >82% yield under 450 nm LEDs by oxidatively quenching CF3I.

Study at a glance

Design
Other — Blue-LED photoredox trifluoromethylation catalyzed by cyclometalated Pt(II) complexes
N
Synthetic photoredox catalysis — no sample N
Population
Alkenes and heteroarenes under Pt(II)/CF3I photoredox conditions
Outcome
Trifluoromethylation yields and oxidative-quenching mechanism

Structured fields used in claim comparison tables when every cited study has a complete layer.

Key findings

Alkene products exceed 82% isolated yield; 1-dodecene finishes in 6 h and N-methylpyrrole in 30 h. No product without Pt or light. Catalysis proceeds by oxidative quenching; catalyst regeneration by sacrificial donor is likely rate-limiting, with >1.43 eV driving force from the substrate radical.

Methodology

Authors irradiated alkenes and heteroarenes with 1 mol% Pt(II), CF3I, and an amine base under blue LEDs, then measured photoluminescence quenching and compared yields with Ru and Ir photoredox standards.

Limitations

Heteroarene yields are only moderate; the paper does not invent a new CF3 reagent or run a process photochemistry scale-up.

How this study connects

Role on claims

Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.

  • SupportsPhotochemistryconcept

    This library holds 10 empirical chemistry papers on photochemistry with isolated findings, rates or spectra rather than reviews.

    Evidence for the claim as stated.

  • SupportsPhotochemistryconcept

    Cyclometalated Pt(II) complexes trifluoromethylate unactivated alkenes in >82% yield under 450 nm LEDs by oxidatively quenching CF3I.

    Evidence for the claim as stated.

  • SupportsPhotochemistryconcept

    Quantum yield, wavelength and quencher identity vary widely; a 'photocatalyst' can be a chain initiator rather than a closed cycle.

    Evidence for the claim as stated.

  • Photoluminescence quenching of a cyclometalated Pt(II) complex is a mechanistic tool, not a sensor calibration. With 1 mol% Pt(II), CF₃I and an amine under blue LEDs, alkene products exceed 82% isolated yield; 1-dodecene finishes in 6 h and N-methylpyrrole in 30 h; no product without Pt or light. Catalysis proceeds by oxidative quenching; regeneration by the sacrificial donor is likely rate-limiting, with >1.43 eV driving force from the substrate radical. Heteroarene yields are only moderate.

    Evidence for the claim as stated.

  • Turn-on sensing, turn-off sensing, FRET photocatalysis and photoluminescence quenching of a molecular catalyst are four fluorescence experiments. Ag/Au clusters raise ΦF 3.28% → 12.89% to report nM FQs; phage carbons quench to LOD 8.0 μM Fe³⁺; TB-Zn-CP quenches to 26.3 ppb picric acid; TPE cages donate to RhB (ΦET 77%/58%) to drive 97% cyclisation; Pt(II) PL quenching assigns oxidative quenching for >82% alkene CF₃ products. 'Fluorescence showed it worked' does not travel among those papers.

    Evidence for the claim as stated.

Open questions

Tensions this paper is part of

From concept pages' “where studies disagree.” Disagreement means the same question; scope means different assays, populations, or outcomes.

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