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Cardiovascular

Does coconut oil raise LDL like butter?

Khaw KT, Sharp SJ, Finikarides L, et al. · BMJ open · 2018

Open access · cc by · source: Europe PMC

In 96 healthy adults, 50 g/day butter for 4 weeks raised LDL-C by ~0.4 mmol/L versus coconut or olive oil; coconut oil did not differ from olive oil on LDL and raised HDL-C.

Study at a glance

Design
RCT — Community RCT in Cambridgeshire (BBC-recruited) assigning extra virgin coconut oil, extra virgin olive oil, or unsalted butter 50 g/day for 4 weeks
N
N=96 · 96 randomised; 94 attended baseline; 91 completed 4-week follow-up
Population
Healthy volunteers aged 50–75 years without cancer, CVD, diabetes, or lipid-lowering drugs
Outcome
Change in serum LDL-C (primary); other lipids, weight, BP, glucose, CRP

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Key findings

Butter increased LDL-C vs coconut (+0.42 mmol/L) and olive oil (+0.38 mmol/L); coconut vs olive LDL change was −0.04 mmol/L (P=0.74). Coconut raised HDL-C vs butter (+0.18) and olive oil (+0.16). Weight, BMI, adiposity, glucose, and BP did not differ.

Methodology

BBC-recruited Cambridgeshire volunteers aged 50–75 were randomised to extra virgin coconut oil, extra virgin olive oil, or unsalted butter (50 g daily for 4 weeks) with LDL-C as the primary endpoint.

Limitations

Four weeks in healthy volunteers cannot prove coconut oil is heart-safe or that it should replace guideline advice to limit saturated fat; events were not measured.

How this study connects

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