Health behaviour
Do diet and sleep disorders combine to raise death risk?
Open access · cc by · source: Europe PMC
In 23,212 NHANES adults, low Mediterranean-diet scores plus sleep disorders raised all-cause (HR 2.16) and CVD (HR 2.68) mortality, with a significant CVD interaction.
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Study at a glance
- Design
- Cohort — NHANES 2005–2014 prospective mortality follow-up; Cox models of aMED × sleep disorder interaction
- N
- N=23212 · 23,212 NHANES 2005–2014 participants
- Population
- US NHANES adults with diet scores, sleep questionnaires, and mortality linkage
- Outcome
- All-cause, cardiovascular, and cancer mortality; interaction between aMED adherence and sleep disorders
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Do diet and sleep disorders combine to raise death risk?
These passages occur verbatim in the stored paper text. They support the points listed below; they do not verify every statement in the explanation.
23,212 NHANES 2005–2014 individuals were included.
The study included 23,212 individuals in the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2014.
Low aMED plus sleep disorders: all-cause HR 2.16 and CVD HR 2.68.
participants with lower aMED and presence of sleep disorders had significantly higher risk of all-cause mortality and cardiovascular-related mortality (HR, 2.16, 95% CI, 1.49–3.13, P < 0.0001; HR, 2.68, 95% CI, 1.58–4.54, P = 0.0003).
Key findings
Lower aMED plus sleep disorders: all-cause HR 2.16 (1.49–3.13) and CVD HR 2.68 (1.58–4.54). Interaction was significant for CVD mortality (p=0.033) but not all-cause (p=0.184) or cancer (p=0.955).
Methodology
Scored alternative Mediterranean diet (aMED, 9 points), assessed sleep disorder and sleep hours by questionnaire, and ran Cox models for all-cause, cardiovascular, and cancer death, including aMED × sleep-disorder interaction.
Limitations
Observational NHANES cannot prove changing diet or treating sleep disorders will cut deaths; sleep was self-reported, not polysomnography.
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