Microbiome
Is the gut microbiome the same along the intestine?
Open access · cc by · source: Europe PMC
Swine mucosal and luminal microbiomes differ by gut section, with distinct diversity patterns and bile-acid/SCFA environments.
Key findings
Communities dominated by Firmicutes/Bacteroidetes/Proteobacteria; richness and α/β-diversity differ by section and lumen vs mucosa; ileal bile acids much higher than large intestine.
Methodology
Profiled luminal and mucosa-attached microbiota across swine intestinal sections and measured bile acids and SCFAs.
Limitations
Does not prove identical patterns in every human diet or disease state.
How this study connects
Role on claims
Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.
Strain-level gene content varies a lot within the same gut species — species labels are coarse.
Even within the same named gut species, strain-level gene content varies substantially among healthy people—so species labels alone understate functional diversity.
Scope note — different scale — mucosal vs luminal niches along the gut
Limits the claim's scope: a different population, assay, or outcome.
History
When this study was placed
Dated entries from the concept change log — when this paper was added or removed as support, challenge, or qualifier on a claim.
Placed as a scope qualifier on Microbiome
Even within the same named gut species, strain-level gene content varies substantially among healthy people—so species labels alone understate functional diversity.
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Same topic cluster — not a recommendation engine.