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Marital status and cancer survival trends

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Among Norwegian cancer patients, never-married people—especially older men—showed growing excess mortality versus married peers over decades.

Source

Changes over time in the effect of marital status on cancer survival

Kravdal H, Syse A · BMC public health · 2011

doi.org/10.1186/1471-2458-11-804Read the full paper ↗54 citationscc by

Study at a glance

Design
Cohort — Norwegian Cancer Registry cases 1953 onward; marital status and cancer outcomes over time
N
N=441556 · Women and men aged 30–89 at diagnosis
Population
Norwegian adults diagnosed with cancer
Outcome
Cancer outcomes associated with marital status, and how that association changed over time

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Marital status and cancer survival trends

These passages occur verbatim in the stored paper text. They support the points listed below; they do not verify every statement in the explanation.

Never-married men had ~3.4 percentage-point per decade rise in excess mortality.

For men, a statistically significant increase in excess mortality of about 3.4 percentage points per decade was observed for the never-married.

Study included 441,556 patients aged 30–89.

Our study is restricted to the 441 556 women and men who were 30-89 years old when they were diagnosed with a first tumor of one of the following 13 forms between 1970 and 2007: stomach, colon, rectal, pancreatic, lung, breast (females only), cervical, uterine, ovarian, prostate, or bladder cancer, malignant melanoma, or central nervous system tumors.
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What they did

Using Cancer Registry data on 441,556 adults aged 30–89 with first tumours of 13 sites (1970–2007), authors modelled excess mortality by marital status over time, adjusting for age, education, site, stage, and time since diagnosis.

What they found

All unmarried groups had excess mortality vs married; for men, never-married excess mortality rose ~3.4 percentage points per decade, mainly among those diagnosed after age 70.

The limits

What it doesn't show

Causal pathways (treatment access, cohabitation misclassification, social support) and whether interventions closing the gap would improve survival.

Key terms

Excess mortality
Extra death risk relative to a reference group (here, married patients).
Cancer registry cohort
Population-based ascertainment of cancer cases over calendar time.
Never-married
Patients recorded as never having been married at relevant follow-up.
Stage
Extent of cancer at diagnosis used as a covariate.
Cohabitation
Living with a partner without marriage, which may blur marital categories.
Oncology outcomes
Survival and mortality results after cancer diagnosis.

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Common questions

Who was included?

441,556 Norwegian adults 30–89 with a first tumour of one of 13 cancer forms, 1970–2007.

What trend stood out for men?

Never-married excess mortality rose about 3.4 percentage points per decade.

Where was the never-married disadvantage concentrated?

Mainly among those diagnosed above age 70.

Did divorced patients show the same rising gap?

Authors described a more stable pattern among the divorced.

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