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What did McClintock argue in 1961?

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Wu shows that McClintock drew parallels between maize controlling elements and the bacterial operon, but Jacob and Monod recast her contribution as mere mobility.

Source

Controlling systems and controlling legacies: Barbara McClintock's 1961 conversation with two bacterial geneticists

Wu Q · History and philosophy of the life sciences · 2024

doi.org/10.1007/s40656-024-00631-9Read the full paper ↗1 citationscc by

Study at a glance

Design
Qualitative / archival — Close reading of 1961 papers, correspondence, and lectures on McClintock vs Jacob–Monod
N
Intellectual history of controlling elements and the operon; not a sample N
Population
Barbara McClintock’s maize controlling systems and bacterial geneticists’ reception in 1961
Outcome
Under-recognised control-system interpretation versus mobility-focused Nobel memory

Structured fields used in claim comparison tables when every cited study has a complete layer.

What they did

Using 1961 papers, correspondence, and lecture manuscripts, the article contrasts Ac-Ds/Spm cytology with the regulator-operator-episome molecular story and the split Nobel memory (1965 vs 1983).

What they found

Keller centred mobile elements; Comfort centred control. Wu argues control systems were the gender-neutral science that stayed under-recognised—the Matilda effect in intellectual form.

The limits

What it doesn't show

This is a history of one conversation and its prizes, not a molecular re-analysis of transposition. It does not claim McClintock discovered the operon.

Key terms

Controlling elements
McClintock’s maize systems that regulated gene expression, not only moved.
Operon
Jacob and Monod’s bacterial regulator-operator-structural-gene control chain.
Matilda effect
Under-recognition of a woman scientist, here also intellectual and epistemological.
Episome
Mobile bacterial element Jacob likened to McClintock’s controllers, flattening her control claim.

Flashcards

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Research intelligence for this paper

See its role on concept claims, tensions it is part of, placement history, and related discoveries.

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Quiz yourself

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McClintock’s own focus, per Comfort/Wu?

Common questions

Jumping genes only?

That is the Nobel/Keller story; McClintock thought control mattered more.

Why 1961?

She tried to win recognition by paralleling maize systems with the operon.

Did prizes settle it?

1965 credited bacterial control to Jacob and Monod; 1983 locked McClintock to mobility.

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