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Pathogens in Nairobi water and feces

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Dog feces carried the most enteric pathogens among hosts sampled in a Nairobi informal area.

Source

Enteric Pathogens in Humans, Domesticated Animals, and Drinking Water in a Low-Income Urban Area of Nairobi, Kenya

Daly SW, Chieng B, Araka S, et al. · Environmental science & technology · 2024

doi.org/10.1021/acs.est.4c10041Read the full paper ↗11 citationscc by

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Pathogens in Nairobi water and feces

These passages occur verbatim in the stored paper text. They support the points listed below; they do not verify every statement in the explanation.

Study setting?

Dagoretti South subcounty of Nairobi, Kenya in 2019

Detection platform?

TaqMan Array Cards (TACs)
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What they did

Used TaqMan Array Cards and microbial source tracking on feces and drinking water from Dagoretti South, Nairobi, in 2019.

What they found

Dogs had a mean 15.5 pathogen targets per sample; MST markers leaked across hosts (HF183 70% sensitive); canine feces are an under-managed exposure route.

The limits

What it doesn't show

Does not prove that dog-feces interventions would reduce child diarrhea in this community.

Key terms

Enteric pathogen
Microbe that infects the gut, often via feces or water.
MST
Microbial source tracking of fecal contamination.
HF183
Marker often used for human fecal Bacteroides.
TaqMan Array Card
Multiplex PCR card for many pathogen genes at once.
WASH
Water, sanitation, and hygiene interventions.
Zoonotic
Pathogen that can jump from animals to people.

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Highest mean pathogen count was in:

Common questions

Where?

Dagoretti South, Nairobi, Kenya.

Top pathogen host?

Dogs (mean 15.5 targets).

HF183 sensitivity?

70.0%.

Avian GFD sensitivity?

82.5%.

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