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Treatment adherence

English TBQ validation

Tran VT, Harrington M, Montori VM, et al. · BMC medicine · 2014

Open access · cc by · source: Europe PMC

Researchers adapted and validated an English Treatment Burden Questionnaire for chronic illness across US/UK/Canada/Australia using PatientsLikeMe.

Key findings

TBQ showed a dominant first factor (87% variance), high item completion, and validity as a cross-condition treatment-burden measure—the first such English instrument in these countries.

Methodology

After pretesting and wording changes, 3,000 PatientsLikeMe members were invited; 610 completed the English TBQ; factor structure, construct validity, and reliability were assessed.

Limitations

Online chronic-illness volunteers may not represent all clinic populations, and burden scores are self-report.

How this study connects

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