Cell signalling
LOX1 oxylipins close stomata in defense
Open access · cc by · source: Europe PMC
Guard-cell LOX1 drives ABA-independent stomatal closure that limits Pseudomonas colonization.
How this study connects
Role on claims
Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.
Multiple empirical papers in this library examine cell signalling with mechanistic biological findings.
Evidence for the claim as stated.
LOX1 is guard-cell expressed; lox1 mutants show >10-fold more Pst growth and impaired flg22/Pst-induced stomatal closure.
Evidence for the claim as stated.
Systems and scales differ across cell signalling studies (species, tissues, methods), so mechanisms should not be over-generalised.
Evidence for the claim as stated.
Open questions
Tensions this paper is part of
From concept pages' “where studies disagree.” Disagreement means the same question; scope means different assays, populations, or outcomes.
Systems and scales differ across cell signalling studies (species, tissues, methods), so mechanisms should not be over-generalised.
- Supports · Shared class A GPCR activation path
- Supports · How does USP8 turn on Smoothened?
Study at a glance
- Design
- Animal / in-vitro — Arabidopsis LOX1 mutants tested for stomatal immunity and Pst colonization
- N
- Plant mutant phenotyping; no single primary analytic N in stored text
- Population
- Arabidopsis thaliana (lox1 mutants vs wild type/complemented lines)
- Outcome
- Stomatal closure and Pst leaf colonization controlled by LOX1/oxylipins
Structured fields used in claim comparison tables when every cited study has a complete layer.
Inspect source passages
LOX1 oxylipins close stomata in defense
These passages occur verbatim in the stored paper text. They support the points listed below; they do not verify every statement in the explanation.
lox1 mutants had more than 10-fold enhanced Pst growth.
The two lox1 mutant lines displayed more than 10-fold enhanced growth of Pst DC3000 as compared to the complemented and WT lines, suggesting that LOX1 participates in the control of bacterial leaf colonization.
lox1 bacterial load?
more than 10-fold enhanced growth of Pst DC3000
Key findings
LOX1 is guard-cell expressed; lox1 mutants show >10-fold more Pst growth and impaired flg22/Pst-induced stomatal closure.
Methodology
Mapped LOX expression to cell types, tested lox1 mutants for Pst growth and stomatal responses to bacteria/PAMPs, and placed the pathway relative to ABA.
Limitations
Does not inventory every oxylipin species in all tissues.
Related papers in this topic
Same topic cluster — not a recommendation engine.