Cell signalling
LOX1 oxylipins close stomata in defense
Open access · cc by · source: Europe PMC
Guard-cell LOX1 drives ABA-independent stomatal closure that limits Pseudomonas colonization.
Study at a glance
- Design
- Animal / in-vitro — Arabidopsis LOX1 mutants tested for stomatal immunity and Pst colonization
- N
- Plant mutant phenotyping; no single primary analytic N in stored text
- Population
- Arabidopsis thaliana (lox1 mutants vs wild type/complemented lines)
- Outcome
- Stomatal closure and Pst leaf colonization controlled by LOX1/oxylipins
Structured fields used in claim comparison tables when every cited study has a complete layer.
Key findings
LOX1 is guard-cell expressed; lox1 mutants show >10-fold more Pst growth and impaired flg22/Pst-induced stomatal closure.
Methodology
Mapped LOX expression to cell types, tested lox1 mutants for Pst growth and stomatal responses to bacteria/PAMPs, and placed the pathway relative to ABA.
Limitations
Does not inventory every oxylipin species in all tissues.
How this study connects
Role on claims
Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.
Multiple empirical papers in this library examine cell signalling with mechanistic biological findings.
Evidence for the claim as stated.
LOX1 is guard-cell expressed; lox1 mutants show >10-fold more Pst growth and impaired flg22/Pst-induced stomatal closure.
Evidence for the claim as stated.
Systems and scales differ across cell signalling studies (species, tissues, methods), so mechanisms should not be over-generalised.
Evidence for the claim as stated.
Open questions
Tensions this paper is part of
From concept pages' “where studies disagree.” Disagreement means the same question; scope means different assays, populations, or outcomes.
Systems and scales differ across cell signalling studies (species, tissues, methods), so mechanisms should not be over-generalised.
- Supports · Shared class A GPCR activation path
- Supports · How does USP8 turn on Smoothened?
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