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Metabolism

What do plant respiratory supercomplexes look like?

Maldonado M, Guo F, Letts JA · eLife · 2021

Open access · cc by · source: Europe PMC

Cryo-EM of Vigna radiata CIII2/CIV/SC III2+IV revealed plant-specific MPP-domain features and coordinated CIII2 motions.

Study at a glance

Design
Animal / in-vitro — Single-particle cryo-EM of plant mitochondrial CIII2, CIV, SC III2+IV
N
N=3 · Three assemblies modeled from Vigna radiata
Population
Vigna radiata mitochondrial respiratory complexes
Outcome
Atomic structures and CIII2 conformational dynamics

Structured fields used in claim comparison tables when every cited study has a complete layer.

Key findings

Plant-specific MPP-domain differences, defined CIV subunits, and long-range coordinated CIII2 movements including the iron-sulfur head domain.

Methodology

Determined single-particle cryo-EM structures of mitochondrial CIII2, CIV, and their supercomplex from mung bean.

Limitations

Plant maps may differ from mammalian complexes; static ensembles undersample full catalysis.

How this study connects

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