Topic
Treatment adherence research, explained
17 open-access treatment adherence studies, each with a flashcard deck and a quiz.
- Is forgetting your pills really just an accident?
Forgetting or running out of chronic medication was very common and was predicted by people's beliefs about needing and affording the drug, so it is not purely accidental.
- Does early, guideline-true physical therapy cut back-pain costs?
Among 753,450 MHS adults with new LBP, early guideline-adherent PT (17,175 people) tracked less imaging, injections, surgery, and opioids and about 60% lower 2-year LBP-related costs.
- Do heart texts improve lifestyle adherence?
A text-and-internet cardiac rehab program improved short-term lifestyle adherence after CHD, but the benefit faded by 6 months.
- English TBQ validation
Researchers adapted and validated an English Treatment Burden Questionnaire for chronic illness across US/UK/Canada/Australia using PatientsLikeMe.
- PrEP adherence in Partners PrEP
In a Partners PrEP adherence substudy, median pill-count and MEMS adherence exceeded 97%, and counseling restored most low adherers to ≥80%.
- TB pillbox reminders beat SMS for doses
In a China cluster RCT, medication-monitor reminders cut poor TB adherence 40–50%, while text messages mainly reduced loss to follow-up.
- Digital pills cut blood pressure faster
Patients with uncontrolled hypertension and type 2 diabetes using digital medicines had larger 4-week SBP drops than usual care.
- Doctor communication training helps hypertension care
Training physicians in communication skills improved hypertensive patients’ health literacy, blood pressure control, adherence, and self-efficacy in an Iranian RCT.
- Can teaching doctors to communicate better lower blood pressure?
In a Mashhad RCT of 240 uncontrolled hypertensive patients and 35 physicians, communication-skills training improved BP control, health literacy, adherence, and self-efficacy vs usual care.
- Did home HIV testing and immediate ART work in rural KwaZulu-Natal?
In 10 TasP clusters, 77% of 12,894 adults were contacted and HIV prevalence was 30.5%, but only 47.5% of untreated positives reached clinic care within 6 months.
- Does wireless BP monitoring boost patient activation’s benefits?
In hypertensive adults, a wireless self-monitoring program strengthened links between rising patient activation and better behaviours/BP control.
- ALICE pillbox app RCT
A Spanish tablet pillbox app improved self-reported adherence and reduced missed doses over 3 months in older adults on multiple medicines.
- Real-world tofersen lowers neurofilaments in SOD1-ALS
In 24 German early-access SOD1-ALS patients, tofersen slowed ALSFRS-R decline versus pre-treatment and cut serum NfL and CSF pNfH, but CSF pleocytosis was common.
- Can phages salvage relapsing S. aureus knee replacements?
Three elderly patients with dead-end relapsing S. aureus prosthetic knee infection improved after DAIR plus an intra-articular three-phage cocktail and suppressive antibiotics.
- Join2move usage drop-off
Patients with knee/hip OA used Join2move less than intended: 94% started, 46% hit 6/9 modules, only 19% finished all nine.
- What real-world harms show up with imipenem/cilastatin?
Among 2,574 FAERS reports, imipenem/cilastatin AEs clustered in older men, often within 3 days, with strong signals for delirium, disorganised speech, and some unlabeled events such as cerebral atrophy.
- How might atropine slow experimental myopia?
In form-deprived mice, atropine drops cut axial elongation and ECM remodeling, restored choroid/sclera thickness and CVI, lowered HIF-1α, and protected hypoxic scleral fibroblasts via P53/β-catenin pathways.