Soybean GWAS for protein and oil

Genome-wide SNPs in 298 soybean accessions associate with seed protein and oil content.

Source

A genome-wide association study of seed protein and oil content in soybean

Hwang EY, Song Q, Jia G, et al. · BMC genomics · 2014

Study at a glance

Design: Computational / modelling — GWAS of soybean germplasm SNPs for seed protein and oil with LD/structure estimation
N: N=298 · 298 germplasm accessions; 31,954 QC SNPs
Population: Soybean germplasm accessions
Outcome: SNP associations with seed protein and oil content

Structured fields used in claim comparison tables when every cited study has a complete layer.

What they did

Genotyped soybean germplasm with tens of thousands of SNPs, estimated LD and population structure, and ran GWAS for seed protein and oil.

31,954 QC SNPs across ~86% of the genome; euchromatic LD (r²) fell to 0.2 by ~360 Kbp; protein content varied ~35–50% across accessions.

The limits

Does not prove causal genes without functional follow-up; field environments were limited.

Key terms

GWAS: Genome-wide association study linking markers to traits.
Linkage disequilibrium: Non-random allele associations that set mapping resolution.
SNP: Single-nucleotide polymorphism marker.
Euchromatin: Gene-rich genome regions with faster LD decay.
QTL: Genomic region affecting a quantitative trait.
Germplasm: Diverse accessions used as association panel.

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QC SNPs:

Common questions

How many QC SNPs?

31,954.

How many accessions?

298.

Euchromatic r²=0.2 distance?

About 360 Kbp.

Protein range?

About 35–50%.