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CPK3/6 mediate ABA guard-cell signaling

Calcium-dependent kinases CPK3 and CPK6 act in ABA control of guard-cell anion/Ca²⁺ channels and stomatal closure.

Source

CDPKs CPK6 and CPK3 function in ABA regulation of guard cell S-type anion- and Ca(2+)-permeable channels and stomatal closure

Mori IC, Murata Y, Yang Y, et al. · PLoS biology · 2006

doi.org/10.1371/journal.pbio.0040327Read the full paper ↗446 citationscc by

What they did

Identified guard-cell CDPKs, isolated cpk3/cpk6 mutants, and measured ion-channel and stomatal responses to ABA.

What they found

Among 34 Arabidopsis CDPKs, CPK3 and CPK6 function in ABA-activated S-type anion and Ca²⁺-permeable channels.

The limits

What it doesn't show

Does not map every CDPK substrate in all cell types.

Key terms

CDPK
Calcium-dependent protein kinase.
ABA
Abscisic acid stress hormone.
Guard cell
Cell pair forming the stomatal pore.
S-type anion channel
Slow anion channel for stomatal closure.
CPK3/CPK6
Guard-cell-expressed CDPK genes.
Ca²⁺ signal
Calcium second messenger in ABA signaling.

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Quiz yourself

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CDPK genes:

Common questions

Arabidopsis CDPK gene count?

34.

Key genes?

CPK3 and CPK6.

Hormone?

ABA.

Outputs?

Anion/Ca²⁺ channels and stomatal closure.

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