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Aloe vera medicinal pathway transcriptome

De novo root and leaf transcriptomes highlight saponin and anthraquinone metabolism genes.

Source

De novo sequencing, assembly and characterisation of Aloe vera transcriptome and analysis of expression profiles of genes related to saponin and anthraquinone metabolism

Choudhri P, Rani M, Sangwan RS, et al. · BMC genomics · 2018

doi.org/10.1186/s12864-018-4819-2Read the full paper ↗33 citationscc by

What they did

Illumina RNA-seq of Aloe vera root and leaf with Trinity assembly and pathway annotation.

What they found

~43k CDS per tissue with extensive annotation tied to secondary-metabolite pathways.

The limits

What it doesn't show

Does not chemically quantify every metabolite or prove each enzyme activity.

Key terms

De novo transcriptome
Assembly without a reference genome.
CDS
Predicted coding sequence.
Saponin
Glycoside secondary metabolite.
Anthraquinone
Aromatic Aloe metabolite.
Unigene
Clustered non-redundant transcript.
Secondary metabolism
Specialized plant biosynthetic pathways.

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Topic:

Common questions

Tissues?

Root and leaf.

Assembler?

Trinity.

Focus?

Saponin/anthraquinone.

Organism?

Aloe vera.

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