Topic
Metabolism research, explained
14 open-access metabolism studies, each with a flashcard deck and a quiz.
- What do plant respiratory supercomplexes look like?
Cryo-EM of Vigna radiata CIII2/CIV/SC III2+IV revealed plant-specific MPP-domain features and coordinated CIII2 motions.
- What nutrients are actually available inside tumors?
Absolute metabolomics of >118 metabolites shows murine tumor interstitial fluid differs from plasma, and tumor type, location, and diet reshape local nutrient pools.
- What extreme physiologies does the painted turtle genome encode?
The western painted turtle genome informs evolution of extreme anoxia and freeze tolerance in a slowly evolving vertebrate lineage.
- Ketone BHB eases colitis via STAT6-driven M2 macrophages
IBD mucosa has lower β-hydroxybutyrate; giving BHB reduces DSS colitis severity by promoting STAT6-dependent M2 macrophage programs and mucosal repair.
- What can a wild Medicago genome teach about stress tolerance?
A highly complete Medicago ruthenica genome provides genetic resources for environmental-stress tolerance missing from yield-focused cultivated alfalfa.
- How does ZFP36 reshape metabolism after growth signals?
Growth factors induce ZFP36, which binds and decays metabolic enzyme/transporter mRNAs—especially Eno2—tuning glycolytic metabolism.
- Salmon fat-cell differentiation transcriptome
Atlantic salmon adipose SVF cells progress through proliferative then adipogenic expression programs.
- Does the MEP pathway feed ginsenoside production?
Transcriptomics implicates the chloroplastic MEP pathway—highlighting IspD—in ginsenoside biosynthesis beyond the classic MVA route.
- Folliculin tunes mTORC1 toward TFE3
FLCN–RagC signaling makes mTORC1 substrate-selective for TFE3 phosphorylation under amino-acid cues.
- Do sugar-coated proteins feed Ewing sarcoma?
A zebrafish EWSR1-FLI1 model produced CD99+ small-round-cell tumors with MAPK/ERK on; blocking heparan sulfate with Surfen reduced ERK1/2 signaling and tumorigenicity in vitro and in vivo.
- Can cable-row HIIT train a kayaker’s heart?
In 24 well-trained male kayakers, 8 weeks of resistance-type HIIT and paddling HIIT both improved cardiac function and 500-m performance more than usual paddling; only RHIIT also raised maximum strength.
- How do Cryptosporidium oocysts survive outside hosts?
Oocyst transcriptomes reveal metabolic features that help Cryptosporidium parvum endure environmental stresses without nutrient supply.
- Aloe vera medicinal pathway transcriptome
De novo root and leaf transcriptomes highlight saponin and anthraquinone metabolism genes.
- Does childhood body size itself raise colorectal cancer risk?
MR of UK Biobank and 125,478 CRC participants suggests early-life larger body size raises CRC odds only until adult BMI is accounted for.