Healthy lifestyle and multimorbidity risk
Healthier lifestyle scores tracked lower CVD and diabetes risk and lower multimorbidity transitions.
Source
Lifestyle factors and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study
Study at a glance
- Design
- Cohort — EPIC multinational prospective cohort; healthy lifestyle index
- N
- N=291778 · 64% women; median follow-up 11.0 years
- Population
- EPIC adults free of cancer, CVD, and T2D at baseline across European centres
- Outcome
- Incident cancer, CVD, T2D, and subsequent multimorbidity by lifestyle index
Structured fields used in claim comparison tables when every cited study has a complete layer.
What they did
A multinational prospective cohort related a healthy lifestyle index and component behaviours to cancer, CVD, type 2 diabetes, and subsequent multimorbidity.
What they found
Over median 11.0 years, 3244 people developed multimorbidity. Higher HLI was inversely associated with CVD (HR 0.77 per 3 units) and T2D (HR 0.67), less so with cancer (HR 0.89).
The limits
What it doesn't show
Observational lifestyle scores remain open to residual confounding; this is not a randomised lifestyle trial.
Key terms
- Multimorbidity
- ≥2 of cancer, CVD, or T2D.
- HLI
- Composite healthy lifestyle index.
- Hazard ratio
- Relative event risk.
- Cardiometabolic disease
- CVD and type 2 diabetes.
- Incidence rate
- Events per person-time.
- Prospective cohort
- Follow-up of disease-free participants.
Flashcards
Research intelligence for this paper
See its role on concept claims, tensions it is part of, placement history, and related discoveries.
Quiz yourself
Events:
Common questions
Multimorbidity N?
3244.
Follow-up?
11.0 years median.
CVD HR per 3 HLI?
0.77.
T2D HR?
0.67.
More on Health behaviour