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How do Sinocyclocheilus genomes record cave life?

Sinocyclocheilus cavefish genomes reveal troglomorphic adaptations such as eye degeneration and albinism, paralleling and differing from Astyanax.

Source

The Sinocyclocheilus cavefish genome provides insights into cave adaptation

Yang J, Chen X, Bai J, et al. · BMC biology · 2016

doi.org/10.1186/s12915-015-0223-4Read the full paper ↗188 citationscc by

What they did

Sequenced cave/surface Sinocyclocheilus genomes and compared gene content/expression for cave-related traits.

What they found

Genomic/transcriptomic signatures of eye degeneration and pigmentation loss; some mechanisms differ from Astyanax; constructive cave traits also suggested.

The limits

What it doesn't show

Does not prove a single universal cave-adaptation gene across all fish.

Key terms

Troglomorphic
Cave-associated traits like eye loss/albinism.
Sinocyclocheilus
Chinese karst cavefish genus.
Astyanax
Classic Mexican cavefish model.
Albinism
Loss of pigmentation.

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Focus adaptations

Common questions

Key phenotypes?

Eye degeneration, albinism, etc.

Compared to?

Astyanax cavefish.

Habitat?

SW China karst caves.

Only regressive traits?

Also constructive features suggested.

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