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How do Sinocyclocheilus genomes record cave life?

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Sinocyclocheilus cavefish genomes reveal troglomorphic adaptations such as eye degeneration and albinism, paralleling and differing from Astyanax.

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The Sinocyclocheilus cavefish genome provides insights into cave adaptation

Yang J, Chen X, Bai J, et al. · BMC biology · 2016

doi.org/10.1186/s12915-015-0223-4Read the full paper ↗188 citationscc by

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How do Sinocyclocheilus genomes record cave life?

These passages occur verbatim in the stored paper text. They support the points listed below; they do not verify every statement in the explanation.

What adaptation context is studied?

adaptation to dark subterranean life among other groups of distinct but closely-related cavefishes.

What characters puzzle biologists?

biologists have long puzzled over these troglomorphic characters []
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What they did

Sequenced cave/surface Sinocyclocheilus genomes and compared gene content/expression for cave-related traits.

What they found

Genomic/transcriptomic signatures of eye degeneration and pigmentation loss; some mechanisms differ from Astyanax; constructive cave traits also suggested.

The limits

What it doesn't show

Does not prove a single universal cave-adaptation gene across all fish.

Key terms

Troglomorphic
Cave-associated traits like eye loss/albinism.
Sinocyclocheilus
Chinese karst cavefish genus.
Astyanax
Classic Mexican cavefish model.
Albinism
Loss of pigmentation.

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Focus adaptations

Common questions

Key phenotypes?

Eye degeneration, albinism, etc.

Compared to?

Astyanax cavefish.

Habitat?

SW China karst caves.

Only regressive traits?

Also constructive features suggested.

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