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iCBT for depression in diabetes

Unmodified clinician-supported iCBT beat treatment-as-usual on depression, anxiety, distress, and diabetes-specific distress in adults with diabetes.

Source

Web-Based Cognitive Behavior Therapy for Depression in People With Diabetes Mellitus: A Randomized Controlled Trial

Newby J, Robins L, Wilhelm K, et al. · Journal of medical Internet research · 2017

doi.org/10.2196/jmir.7274Read the full paper ↗79 citationscc by

What they did

After screening, 106 adults with diabetes and depression were randomized to a 6-lesson internet CBT program or treatment-as-usual wait; 91 provided baseline data for ITT analyses. Outcomes included PHQ-9, GAD-7, K-10, PAID, and related measures at posttreatment.

What they found

iCBT produced moderate between-group benefits on PHQ-9 (Hedges g=0.78) and GAD-7 (g=0.72), plus large effects on diabetes distress and general distress. About 66% completed all six lessons; 51% of iCBT completers with data showed reliable PHQ-9 improvement vs 18% of TAU.

The limits

What it doesn't show

Self-reported glycemic control (HbA1c) did not show a clear between-group benefit. Sample sizes shrink at follow-up, and results are for a supported Australian virtual clinic rather than fully unguided public apps.

Key terms

iCBT
Internet-delivered cognitive behavior therapy program.
TAU
Treatment as usual / wait comparison during the intervention window.
PAID
Problem Areas in Diabetes scale for diabetes-specific distress.
Reliable change
Individual improvement beyond measurement error on PHQ-9.
Hedges g
Bias-adjusted standardized between-group effect size.
Diabetes mellitus comorbidity
Depression occurring alongside type 1 or type 2 diabetes.

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What was the experimental treatment?

Common questions

Who was randomized?

106 eligible adults to iCBT (n=49) or TAU (n=57).

Did anxiety improve vs TAU?

Yes—GAD-7 between-group g≈0.72.

Did depression improve vs TAU?

Yes—PHQ-9 between-group g≈0.78.

Was the program diabetes-tailored?

No—authors emphasize an unmodified depression iCBT program.

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