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Host–pathogen

Can a bedside score flag deadly viral pneumonia?

Guo L, Wei D, Zhang X, et al. · Frontiers in microbiology · 2019

Open access · cc by · source: Europe PMC

In 528 viral pneumonia admissions, MuLBSTA (cut-off 12) stratified 90-day mortality better than CURB-65 (AUROC 0.773 vs 0.717).

Study at a glance

Design
Cohort — Hospital viral pneumonia cohort; MuLBSTA logistic score for 90-day mortality
N
N=528 · Training 423 / testing 105
Population
Hospitalized adults with viral pneumonia at RuiJin Hospital, Shanghai
Outcome
90-day in-hospital mortality risk stratification (MuLBSTA vs CURB-65)

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Key findings

76/528 (14.4%) died by 90 days. Top weighted factors included multilobular infiltrates (5 pts) and lymphopenia (4 pts). Sensitivity/specificity ~0.78 at cut-off 12.

Methodology

Recruited viral pneumonia patients, built a weighted logistic score (MuLBSTA) on a training split, and validated discrimination including vs CURB-65.

Limitations

Single-center derivation; score predicts risk, not treatment benefit from any specific therapy.

How this study connects

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