Chemical exposure
Child chemical mixtures and ADHD scores
Open access · cc by · source: Europe PMC
A childhood phthalate mixture, weighted toward DEHP metabolites, tracked higher ADHD scores, mainly in autistic children.
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Child chemical mixtures and ADHD scores
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62 chemicals were analyzed in urine.
A total of 62 trace organic chemicals were analyzed in urine
80.1% of study children were males.
The majority of the study children were males (80.1%)
Key findings
Phthalate mixtures associated with hyperactivity/impulsivity; signals were strongest in children with autism; 43 chemicals with >70% detection entered models.
Methodology
Measured 62 urinary chemicals in 2- to 5-year-olds from CHARGE (ASD, developmental delay, or typical development) and linked mixtures to Aberrant Behavior Checklist ADHD scores with WQS regression.
Limitations
Cross-sectional design cannot rule out reverse causation from autism-related diets and product use.
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