Chemical exposure
Pregnancy PFAS and lead track lower birth weight
Open access · cc by · source: Europe PMC
In Cincinnati’s HOME Study, PFAS, lead, and organophosphate pesticides associated with lower birth weight; phthalates and BPA did not.
Key findings
Nine phthalates plus BPA averaged +1 g per 10-fold exposure; the PFAS class averaged −11 g; all 5 PFAS trended toward lower weight; smoking cut birth weight 210 g.
Methodology
Used Bayesian hierarchical linear models (and LASSO/Elastic Net) on 272 of 389 singleton births with gestational biomarkers at ~16 and 26 weeks.
Limitations
Does not prove mechanisms, model chemical-class interactions, or capture nonlinear thresholds.
How this study connects
Role on claims
Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.
In Cincinnati’s HOME Study, PFAS, lead, and organophosphate pesticides associated with lower birth weight; phthalates and BPA did not.
Evidence for the claim as stated.
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