Particulate matter
2012 Colorado wildfire PM raised asthma visits
Open access · cc by · source: Europe PMC
During a 32-day 2012 fire period, modeled PM2.5 associated with asthma/wheeze and COPD ED visits; cardiovascular associations were largely null.
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2012 Colorado wildfire PM raised asthma visits
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Analyses spanned 32 observations per stratum from June 5 to July 6, 2012.
The analyses spanned from June 5, 2012 to July 6, 2012, thus resulting in 32 observations per stratum.
Were cardiovascular associations consistent?
Overall, the cardiovascular disease effect estimates in our study were fairly consistent with no association although some confidence intervals were wide.
Key findings
Asthma/wheeze 24-h mean OR 1.04 per 5 μg/m³; COPD OR 1.05 per 5 μg/m³. 1-h max ORs were 1.01 per 10 μg/m³. Cardiovascular estimates were consistent with no association; model absolute bias was ~13 μg/m³ in Denver.
Methodology
A grid-stratified case-crossover linked 1-h max and 24-h mean PM2.5 (fire-smoke model) to Colorado ED/hospitalization codes from 5 June–6 July 2012, controlling day-of-week and temperature.
Limitations
One fire season and wide CVD confidence intervals (low case counts) cannot rule out cardiovascular effects; exposure model bias was large near fires.
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