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Antibiotics hurt bee gut and survival

Tetracycline shrinks the honeybee gut microbiome and elevates mortality after hive return.

Source

Antibiotic exposure perturbs the gut microbiota and elevates mortality in honeybees

Raymann K, Shaffer Z, Moran NA · PLoS biology · 2017

doi.org/10.1371/journal.pbio.2001861Read the full paper ↗386 citationscc by

What they did

Fed worker bees tetracycline, quantified 16S community size/composition, and tracked survival in hive vs lab recovery conditions.

What they found

Four of eight core gut species dropped; elevated mortality in treated bees; germ-free bees did not show the same antibiotic mortality spike.

The limits

What it doesn't show

Does not test every antibiotic class or all hive stressors.

Key terms

Core gut microbiome
Stable set of bee gut bacterial species.
Tetracycline
Antibiotic used in beekeeping contexts.
Dysbiosis
Disrupted microbial community state.
Opportunistic pathogen
Microbe that infects when microbiota/host defenses weaken.
qPCR
Quantitative PCR of bacterial load.
Germ-free bees
Bees lacking normal gut microbiota.

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Quiz yourself

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Core species:

Common questions

Core species count?

Eight.

How many core taxa hit?

Four significantly affected.

Antibiotic?

Tetracycline.

Germ-free contrast?

No antibiotic mortality increase without microbiota.

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