Human body microbiome biogeography
Healthy human body sites host distinct bacterial communities across a massive 16S survey.
Source
Biogeography of the ecosystems of the healthy human body
What they did
Analyzed >24 million 16S reads from 2,983 specimens spanning HMP and related healthy cohorts across many body habitats.
What they found
30 phyla to 929 genera detected; habitats differ strongly; average V3–V5 depth ~8,167 reads.
The limits
What it doesn't show
Does not define disease causality for any taxon.
Key terms
- Biogeography
- Spatial patterns of organism diversity.
- Body habitat
- Anatomical niche sampled for microbes.
- 16S rRNA
- Marker gene for bacterial community profiling.
- HMP
- Human Microbiome Project.
- OTU/genus richness
- Taxonomic diversity measures.
- Endemic vs cosmopolitan
- Habitat-restricted vs widespread taxa.
Flashcards
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Specimens:
Common questions
Read count?
>24 million.
Specimens?
2,983.
HMP subjects?
236.
Genera found?
929.
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