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Histone acylations respond to plant stress

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Rice histone butyrylation and crotonylation mark active chromatin and shift under starvation/submergence.

Source

Dynamics and functional interplay of histone lysine butyrylation, crotonylation, and acetylation in rice under starvation and submergence

Lu Y, Xu Q, Liu Y, et al. · Genome biology · 2018

doi.org/10.1186/s13059-018-1533-yRead the full paper ↗107 citationscc by

Study at a glance

Design
Animal / in-vitro — MS and ChIP-seq mapping of histone Kbu/Kcr in rice vs H3K9ac under metabolic stress
N
Plant chromatin proteomics/ChIP-seq study — no single primary analytic N in stored text
Population
Rice (and related plants) under stress conditions
Outcome
Distribution and stress dynamics of histone butyrylation/crotonylation

Structured fields used in claim comparison tables when every cited study has a complete layer.

What they did

Mapped Kbu/Kcr sites by MS and ChIP-seq in rice and compared to H3K9ac with transcriptomes under stress.

What they found

Many Kcr sites on H3/H4; Kbu/Kcr resemble acetylation distribution and change with metabolic stress.

The limits

What it doesn't show

Does not prove every site is required for a specific stress phenotype.

Key terms

Kbu
Lysine butyrylation.
Kcr
Lysine crotonylation.
H3K9ac
Acetylation mark of active chromatin.
ChIP-seq
Chromatin immunoprecipitation sequencing.
Acylation
Short-chain fatty-acyl histone marks.
Submergence
Flooding stress in plants.

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Topic:

Common questions

Organism?

Rice.

Marks?

Kbu and Kcr.

Stresses?

Starvation/submergence.

Compare to?

H3K9ac.

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