Olive oil intake and CVD risk
Higher olive oil intake tracked lower major CVD events and cardiovascular death in PREDIMED participants.
Source
Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study
Study at a glance
- Design
- Cohort — Observational analysis of olive-oil intake nested in the PREDIMED trial population
- N
- N=7216
- Population
- PREDIMED participants at high cardiovascular risk
- Outcome
- Incident cardiovascular disease and mortality associated with olive-oil intake
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Olive oil intake and CVD risk
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7,216 participants included.
a total of 7,216 participants were included in the present analysis. D
277 major CVD events.
During a median of 4.8 y of follow-up we documented 277 incident cases of major cardiovascular events, 81 cardiovascular deaths, 130 cancer deaths and 323 all-cause deaths. Th
What they did
In 7,216 PREDIMED participants, baseline olive oil intake was related to incident major CVD events and mortality over median 4.8 years.
What they found
Each additional 10 g/day olive oil associated with 13% lower major CVD events (HR 0.87) and 16% lower CV mortality (HR 0.84).
The limits
What it doesn't show
Observational intake contrasts within a trial cohort are not equivalent to randomising olive oil alone; residual confounding possible.
Key terms
- Olive oil
- Key Mediterranean fat source analysed by intake.
- Major CVD events
- Composite hard cardiovascular endpoints.
- Hazard ratio
- Relative risk per intake contrast.
- PREDIMED
- Mediterranean diet randomised trial cohort used here observationally.
- EVOO
- Extra-virgin olive oil.
- Tablespoon (~10 g)
- Intake unit used in models.
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Common questions
N?
7,216.
CVD events?
277.
HR per 10 g/d events?
0.87.
Follow-up?
4.8 years.
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