How do Cryptosporidium oocysts survive outside hosts?
Oocyst transcriptomes reveal metabolic features that help Cryptosporidium parvum endure environmental stresses without nutrient supply.
Source
Transcriptome analysis reveals unique metabolic features in the Cryptosporidium parvum Oocysts associated with environmental survival and stresses
Study at a glance
- Design
- Computational / modelling — Transcriptome profiling of C. parvum oocysts to infer environmental persistence metabolism
- N
- Parasite oocyst transcriptome resource — no single sample N in stored text
- Population
- Cryptosporidium parvum oocysts
- Outcome
- Metabolic features linked to environmental persistence
Structured fields used in claim comparison tables when every cited study has a complete layer.
Inspect source passages
How do Cryptosporidium oocysts survive outside hosts?
These passages occur verbatim in the stored paper text. They support the points listed below; they do not verify every statement in the explanation.
What pathogen was studied?
Cryptosporidium parvum is a globally distributed zoonotic pathogen belonging to the phylum Apicomplexa that contains many important human and animal pathogens, such as Plasmodium , Toxoplasma , Eimeria , Babesi
What stage survives in the environment?
oocysts that can survive in the natural environments for a substantial length of time.
What they did
Profiled C. parvum oocyst transcriptomes to infer metabolic capacity related to environmental persistence.
What they found
Unique metabolic features linked to surviving without nutrients and resisting environmental stresses; oocyst wall protects four sporozoites.
The limits
What it doesn't show
Does not itself invent a new clinical drug regimen.
Key terms
- Oocyst
- Environmentally resistant spore-like stage.
- Cryptosporidium parvum
- Zoonotic apicomplexan pathogen.
- Sporozoite
- Infective cells inside the oocyst.
- Apicomplexa
- Phylum including Plasmodium, Toxoplasma, Cryptosporidium.
Flashcards
0 of 11 answers reviewed
Research intelligence for this paper
See its role on concept claims, tensions it is part of, placement history, and related discoveries.
Quiz yourself
Stage profiled
Common questions
Stage studied?
Oocysts.
How many sporozoites?
Four per oocyst.
Key insight?
Metabolism for nutrient-free environmental survival.
Pathogen group?
Apicomplexa.
More on Metabolism