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How does fish liver gene expression change under confinement stress?

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Microarrays track the time course of gilthead sea bream liver transcriptional responses after confinement stress linked to cortisol biology.

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Use of microarray technology to assess the time course of liver stress response after confinement exposure in gilthead sea bream (Sparus aurata L.)

Calduch-Giner JA, Davey G, Saera-Vila A, et al. · BMC genomics · 2010

doi.org/10.1186/1471-2164-11-193Read the full paper ↗51 citationscc by

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How does fish liver gene expression change under confinement stress?

These passages occur verbatim in the stored paper text. They support the points listed below; they do not verify every statement in the explanation.

What species was studied?

gilthead sea bream ( Sparus aurata ) from parents selected for low- or high-cortisol response also show divergent responses []

What stressor is central?

after handling and exposure to a confinement stressor [,].
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What they did

Used microarray profiling of liver after confinement exposure in Sparus aurata, relating responses to stress/cortisol physiology.

What they found

Time-dependent liver stress-response transcripts; connects to known cortisol and GHR stress sensitivity in this aquaculture species.

The limits

What it doesn't show

Does not itself complete a full breeding program for low-stress fish.

Key terms

Confinement stress
Handling/crowding stressor used in fish physiology.
Cortisol
Primary glucocorticoid stress hormone in fish.
Gilthead sea bream
Sparus aurata aquaculture species.
Microarray
Parallel hybridization assay of many transcripts.

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Species

Common questions

Tissue?

Liver.

Stressor?

Confinement.

Species?

Gilthead sea bream.

Hormone focus?

Cortisol-related stress responses.

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