Nanomaterials
Gamma-made Ag–Se nanoparticles carrying cefotaxime
Open access · cc by · source: Europe PMC
Radiolytic Ag, Se, and Ag–Se nanoparticles (about 11–21 nm) are characterized and loaded with cefotaxime for synergistic antimicrobial tests.
Key findings
Spherical particles averaging 10.95 nm (Ag), 20.54 nm (Se), and 12.69 nm (Ag–Se). Optical densities were recorded at 406, 518, and 420 nm. A radiolytic reduction mechanism at those kGy doses is proposed.
Methodology
Authors reduced 1.0 mM AgNO3 and/or Na2SeO3 with gamma rays (15 kGy Ag/Ag–Se; 10 kGy Se), tracked UV-vis (406/518/420 nm), sized particles by DLS/HR-TEM/XRD, and combined them with cefotaxime for antimicrobial/antibiofilm assays.
Limitations
This is not a randomized clinical UTI trial; membrane-leakage/MIC biology is secondary to the materials characterization for chemistry teaching.
How this study connects
Role on claims
Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.
XRD/TEM size of a fuel-cell catalyst need not match which particles do the electrochemistry. Platinum sputtered onto PEG starts as 1.8 nm primaries; heat treatment at 150 °C on Vulcan carbon yields a bimodal 2.5 ± 0.8 nm and 6.7 ± 1.8 nm distribution, and the larger population dominates oxygen-reduction activity. Gamma-made Ag, Se and Ag–Se particles average 10.95, 20.54 and 12.69 nm by complementary sizing, with UV-vis maxima at 406, 518 and 420 nm — XRD here is one size/phase check among several.
Evidence for the claim as stated.
Silver SPR is a size/composition reporter, not a structure determination. GSH-capped Ag develops SPR at 344–354 nm as TEM diameters go 3.20 → 4.83 → 6.19 nm (36/48/72 h). Aqueous glycerol (10–100%) keeps SPR in 410–450 nm and particles <10 nm up to ~60% glycerol, then SPR and size rise above ~70–80% glycerol (about 10–160 nm). Gamma-made Ag/Se/Ag–Se particles are tracked at 406, 518 and 420 nm with mean sizes 10.95, 20.54 and 12.69 nm.
Evidence for the claim as stated.
GSH-capped Ag uses SEM-EDX beside TEM diameters of 3.20, 4.83 and 6.19 nm (36/48/72 h) and SPR at 344–354 nm; gamma Ag/Se/Ag–Se particles average 10.95, 20.54 and 12.69 nm. Those papers are particle-sizing problems. A different indexed study maps ITO with a 50 nm SECCM pipette: the entire surface is active, only 0.2% of area is reversible (k⁰ ≥ 1 cm s⁻¹), 85.2% has mean k⁰ = 4.2×10⁻² cm s⁻¹, and a weighted average k⁰ ≈ 3.61×10⁻² cm s⁻¹ — activity, not an SEM micrograph.
Evidence for the claim as stated.
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