Innate immunity
Coral gene expression in white syndromes
Open access · cc by · source: Europe PMC
White-syndrome lesions in Acropora hyacinthus show distinct innate-immunity–related expression versus healthy tissue.
Study at a glance
- Design
- Other — RNA-seq of white-syndrome disease, adjacent, and healthy Acropora hyacinthus tissues
- N
- N=16 · Fragments from 16 colonies; analyses with n=8 per tissue group
- Population
- Reef-building coral Acropora hyacinthus colonies in Palau
- Outcome
- Differentially expressed genes separating diseased from healthy coral tissue
Structured fields used in claim comparison tables when every cited study has a complete layer.
Key findings
Hundreds of DEGs separate disease from healthy; healthy vs adjacent are more similar.
Methodology
RNA-seq contrasted disease, adjacent, and healthy coral tissues and called differentially expressed genes.
Limitations
Field disease etiology remains debated; expression ≠ proven causation.
How this study connects
Role on claims
Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.
Multiple empirical papers in this library examine innate immunity with mechanistic biological findings.
Evidence for the claim as stated.
Hundreds of DEGs separate disease from healthy; healthy vs adjacent are more similar.
Evidence for the claim as stated.
Systems and scales differ across innate immunity studies (species, tissues, methods), so mechanisms should not be over-generalised.
Evidence for the claim as stated.
Field disease RNA-seq separates states more cleanly than it names a pathogen. Hundreds of DEGs separated white-syndrome coral tissue from healthy tissue, while adjacent and healthy transcriptomes were more similar — expression differences, not a settled etiology.
Evidence for the claim as stated.
How far a transcriptome may be generalised is itself in dispute in these papers. Tomato red-light findings are not automatically all crops; mixed-yeast dilution rates are experimental; LCL methylation–expression links may not hold in primary tissues; coral DEGs do not settle field etiology.
Evidence for the claim as stated.
Open questions
Tensions this paper is part of
From concept pages' “where studies disagree.” Disagreement means the same question; scope means different assays, populations, or outcomes.
Systems and scales differ across innate immunity studies (species, tissues, methods), so mechanisms should not be over-generalised.
How far a transcriptome may be generalised is itself in dispute in these papers. Tomato red-light findings are not automatically all crops; mixed-yeast dilution rates are experimental; LCL methylation–expression links may not hold in primary tissues; coral DEGs do not settle field etiology.
- Supports · Does red light help tomatoes fight bacteria?
- Supports · What do co-fermenting yeasts express together?
- Supports · Genetics shapes methylation and expression
Related papers in this topic
Same topic cluster — not a recommendation engine.