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Models & animals

What makes a model organism a model organism?

Prieto GI, Fábregas-Tejeda A · History and philosophy of the life sciences · 2026

Open access · cc by · source: Europe PMC

Not just fame or a genome, but versatility: standardized organisms (Drosophila, Xenopus, Arabidopsis) support many targets and strategies over time (T-scope and S-scope).

How this study connects

Role on claims

Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.

  • SupportsModels & animalsconcept

    Model organisms are marked by versatility across targets and strategies over time, not merely fame or a genome.

    Evidence for the claim as stated.

Inspect source passages

What makes a model organism a model organism?

These passages occur verbatim in the stored paper text. They support the points listed below; they do not verify every statement in the explanation.

Why they matter?

Prevailing empirical practices within the biological and biomedical sciences could not be understood without the use of a swathe of so-called model organis

Examples?

fruit fly Drosophila melanogaster , the African clawed frog Xenopus laevis , and the thale cress Arabidopsis thaliana . Recognizing its undeniable heuristi
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Key findings

Versatility is grounded in the fact that model organisms are standardized — material, integrated systems with evolutionary history. That is why they are heuristically and explanatorily central, and why their insights differ from those of non-model experimental organisms.

Methodology

The authors place model organisms at the centre of biomedical practice, distinguish insights they yield from other experimental organisms, and analyse diachronic target versatility and related scopes, noting compatibility with Larraín on representational power.

Limitations

This is philosophy of scientific practice, not a new fly experiment. It does not rank every species.

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