Natural selection
Why isn’t diversity proportional to population size?
Open access · cc by · source: Europe PMC
Natural selection via hitchhiking and background selection constrains neutral diversity, especially in species with larger census sizes.
Key findings
Species with larger Nc show stronger correlation between neutral polymorphism and recombination rate, indicating a larger role for selection in shaping genome-wide diversity.
Methodology
Compared polymorphism–recombination relationships across many species to test how selection shapes linked neutral diversity relative to census size (Nc).
Limitations
Cryptic population structure can still influence variation patterns; mechanisms are inferred comparatively.
How this study connects
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