Natural selection
Hybrid necrosis as plant autoimmunity
Open access · cc by · source: Europe PMC
Arabidopsis hybrid necrosis is a Dobzhansky–Muller incompatibility driven by autoimmune NB-LRR conflict.
Study at a glance
- Design
- Animal / in-vitro — Genetic mapping of necrotic Uk-1×Uk-3 Arabidopsis hybrids to NB-LRR mismatch loci
- N
- Plant hybrid incompatibility genetics; penetrance temperature-dependent — no single sample N
- Population
- Arabidopsis thaliana hybrid and introgression lines (Uk-1×Uk-3)
- Outcome
- DM1/DM2 necessity for autoimmune hybrid necrosis
Structured fields used in claim comparison tables when every cited study has a complete layer.
Key findings
DM1 (Chr5, Uk-3) and DM2 (Chr3, Uk-1) are necessary and sufficient; phenotype fully penetrant at 16°C and suppressed at 23°C.
Methodology
Mapped necrotic Uk-1×Uk-3 hybrids, introgressed DM1/DM2, and linked the phenotype to NB-LRR immune gene mismatch.
Limitations
Does not prove every plant hybrid incompatibility is autoimmune.
How this study connects
Role on claims
Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.
Multiple empirical papers in this library examine natural selection with mechanistic biological findings.
Evidence for the claim as stated.
DM1 (Chr5, Uk-3) and DM2 (Chr3, Uk-1) are necessary and sufficient; phenotype fully penetrant at 16°C and suppressed at 23°C.
Evidence for the claim as stated.
Systems and scales differ across natural selection studies (species, tissues, methods), so mechanisms should not be over-generalised.
Evidence for the claim as stated.
Open questions
Tensions this paper is part of
From concept pages' “where studies disagree.” Disagreement means the same question; scope means different assays, populations, or outcomes.
Systems and scales differ across natural selection studies (species, tissues, methods), so mechanisms should not be over-generalised.
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