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Natural selection

What does Arabidopsis polymorphism look like genome-wide?

Nordborg M, Hu TT, Ishino Y, et al. · PLoS biology · 2005

Open access · cc by · source: Europe PMC

A. thaliana shows clear global population structure and isolation by distance; demography can mimic selection in standard tests.

Key findings

Clear global structure and isolation by distance; selfing does not make it asexual lineages; polymorphism not unusually low; demography can invalidate naive selection tests.

Methodology

Genotyped many markers across hierarchical and worldwide Arabidopsis accessions and analyzed structure, LD, and neutrality statistics.

Limitations

Does not map every selected locus causing adaptation.

How this study connects

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