Circadian biology
Does the plant clock gate auxin responses?
Open access · cc by · source: Europe PMC
The Arabidopsis circadian clock regulates auxin-responsive transcription and gates growth responses to auxin.
Study at a glance
- Design
- Animal / in-vitro — Circadian transcriptomes overlapped with auxin responses; timed auxin transcriptional/growth assays
- N
- Arabidopsis seedling genome-wide profiling — no single organismal N in stored text
- Population
- Arabidopsis thaliana seedlings
- Outcome
- Clock gating of auxin transcriptional responses and growth
Structured fields used in claim comparison tables when every cited study has a complete layer.
Key findings
>10% of seedling genes cycle; auxin-induced genes are enriched for clock regulation; endogenous/exogenous auxin transcriptional responses and auxin-driven growth are clock-gated.
Methodology
Profiled circadian transcriptomes and tested overlaps with auxin-regulated genes, then assayed transcriptional and growth responses to auxin across the day.
Limitations
Does not fully map every clock–auxin molecular node in all tissues or prove clinical relevance outside plants.
How this study connects
Role on claims
Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.
Arabidopsis circadian transcriptomes overlapped auxin-regulated genes: more than 10% of seedling genes cycle, auxin-induced genes are enriched for clock regulation, and both transcriptional responses to auxin and auxin-driven growth are clock-gated. Luciferase or transcriptional reporters across the day are how gating is scored; every clock–auxin node in every tissue is not mapped.
Evidence for the claim as stated.
Clock-gated auxin reporters and Wnt5a TCF reporters both measure transcription, but one asks 'what time of day' (>10% of seedling genes cycle) and the other asks 'which Frizzled is present'. The same luminescence number cannot be compared across a plant growth assay and a mammalian β-catenin pathway.
Evidence for the claim as stated.
Open questions
Tensions this paper is part of
From concept pages' “where studies disagree.” Disagreement means the same question; scope means different assays, populations, or outcomes.
Clock-gated auxin reporters and Wnt5a TCF reporters both measure transcription, but one asks 'what time of day' (>10% of seedling genes cycle) and the other asks 'which Frizzled is present'. The same luminescence number cannot be compared across a plant growth assay and a mammalian β-catenin pathway.
Related papers in this topic
Same topic cluster — not a recommendation engine.