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Circadian biology

Does light control fungal cellulase genes?

Schmoll M, Tian C, Sun J, et al. · BMC genomics · 2012

Open access · cc by · source: Europe PMC

Neurospora photoreceptors WC-1, WC-2 and VVD influence cellulase expression; light-modulated cellulase regulation is conserved in filamentous fungi.

How this study connects

Role on claims

Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.

  • SupportsCircadian biologyconcept

    Multiple empirical papers in this library examine circadian biology with mechanistic biological findings.

    Evidence for the claim as stated.

  • SupportsCircadian biologyconcept

    WC-1, WC-2 and VVD affect cellulase gene expression; light modulation of cellulases appears conserved, likely advantageous in nature.

    Evidence for the claim as stated.

  • SupportsCircadian biologyconcept

    Systems and scales differ across circadian biology studies (species, tissues, methods), so mechanisms should not be over-generalised.

    Evidence for the claim as stated.

Open questions

Tensions this paper is part of

From concept pages' “where studies disagree.” Disagreement means the same question; scope means different assays, populations, or outcomes.

Study at a glance

Design
Animal / in-vitro — Cellulase transcription profiling in photoreceptor mutants under light regimes
N
Fungal photoreceptor mutant expression study — no single sample N in stored text
Population
Fungi with WC-1/WC-2/VVD photoreceptor pathways
Outcome
Light modulation of cellulase gene expression via photoreceptors

Structured fields used in claim comparison tables when every cited study has a complete layer.

Inspect source passages

Does light control fungal cellulase genes?

These passages occur verbatim in the stored paper text. They support the points listed below; they do not verify every statement in the explanation.

Which photoreceptors influence cellulase expression?

photoreceptors WC-1, WC-2 and VVD influence cellulase gene expression.

Is light-modulated cellulase expression unique?

light-modulated expression of cellulolytic enzymes is a conserved phenomenon, most probably providing an evolutionary advantage to filamentous fungi in their natural habitat.
Read passages in the original paper

Key findings

WC-1, WC-2 and VVD affect cellulase gene expression; light modulation of cellulases appears conserved, likely advantageous in nature.

Methodology

Profiled cellulase-related transcription in photoreceptor mutants and compared light effects on cellulolytic enzyme expression.

Limitations

Does not engineer industrial cellulase strains for bioreactors.

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Same topic cluster — not a recommendation engine.