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Circadian biology

Does light control fungal cellulase genes?

Schmoll M, Tian C, Sun J, et al. · BMC genomics · 2012

Open access · cc by · source: Europe PMC

Neurospora photoreceptors WC-1, WC-2 and VVD influence cellulase expression; light-modulated cellulase regulation is conserved in filamentous fungi.

Study at a glance

Design
Animal / in-vitro — Cellulase transcription profiling in photoreceptor mutants under light regimes
N
Fungal photoreceptor mutant expression study — no single sample N in stored text
Population
Fungi with WC-1/WC-2/VVD photoreceptor pathways
Outcome
Light modulation of cellulase gene expression via photoreceptors

Structured fields used in claim comparison tables when every cited study has a complete layer.

Key findings

WC-1, WC-2 and VVD affect cellulase gene expression; light modulation of cellulases appears conserved, likely advantageous in nature.

Methodology

Profiled cellulase-related transcription in photoreceptor mutants and compared light effects on cellulolytic enzyme expression.

Limitations

Does not engineer industrial cellulase strains for bioreactors.

How this study connects

Role on claims

Each row is a claim on a concept or method page where this paper supports, challenges, or qualifies the statement. Roles are hand-checked — not a model guess.

  • SupportsCircadian biologyconcept

    Multiple empirical papers in this library examine circadian biology with mechanistic biological findings.

    Evidence for the claim as stated.

  • SupportsCircadian biologyconcept

    WC-1, WC-2 and VVD affect cellulase gene expression; light modulation of cellulases appears conserved, likely advantageous in nature.

    Evidence for the claim as stated.

  • SupportsCircadian biologyconcept

    Systems and scales differ across circadian biology studies (species, tissues, methods), so mechanisms should not be over-generalised.

    Evidence for the claim as stated.

Open questions

Tensions this paper is part of

From concept pages' “where studies disagree.” Disagreement means the same question; scope means different assays, populations, or outcomes.

Related papers in this topic

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