LOX1 oxylipins close stomata in defense
Guard-cell LOX1 drives ABA-independent stomatal closure that limits Pseudomonas colonization.
Source
An abscisic acid-independent oxylipin pathway controls stomatal closure and immune defense in Arabidopsis
What they did
Mapped LOX expression to cell types, tested lox1 mutants for Pst growth and stomatal responses to bacteria/PAMPs, and placed the pathway relative to ABA.
What they found
LOX1 is guard-cell expressed; lox1 mutants show >10-fold more Pst growth and impaired flg22/Pst-induced stomatal closure.
The limits
What it doesn't show
Does not inventory every oxylipin species in all tissues.
Key terms
- LOX1
- 9-lipoxygenase gene expressed in guard cells.
- Stomata
- Leaf pores that microbes can enter.
- Oxylipin
- Oxygenated fatty-acid signaling molecule.
- flg22
- Flagellin PAMP peptide.
- ABA
- Abscisic acid drought/stress hormone.
- Pst DC3000
- Pseudomonas syringae leaf pathogen.
Flashcards
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lox1 Pst growth:
Common questions
lox1 pathogen phenotype?
>10-fold more Pst growth.
Where is LOX1 expressed?
Guard cells.
PAMP tested?
flg22.
ABA dependence?
Pathway can act independently of ABA.
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