Can a bedside score flag deadly viral pneumonia?
In 528 viral pneumonia admissions, MuLBSTA (cut-off 12) stratified 90-day mortality better than CURB-65 (AUROC 0.773 vs 0.717).
Source
Clinical Features Predicting Mortality Risk in Patients With Viral Pneumonia: The MuLBSTA Score
Study at a glance
- Design
- Cohort — Hospital viral pneumonia cohort; MuLBSTA logistic score for 90-day mortality
- N
- N=528 · Training 423 / testing 105
- Population
- Hospitalized adults with viral pneumonia at RuiJin Hospital, Shanghai
- Outcome
- 90-day in-hospital mortality risk stratification (MuLBSTA vs CURB-65)
Structured fields used in claim comparison tables when every cited study has a complete layer.
What they did
Recruited viral pneumonia patients, built a weighted logistic score (MuLBSTA) on a training split, and validated discrimination including vs CURB-65.
What they found
76/528 (14.4%) died by 90 days. Top weighted factors included multilobular infiltrates (5 pts) and lymphopenia (4 pts). Sensitivity/specificity ~0.78 at cut-off 12.
The limits
What it doesn't show
Single-center derivation; score predicts risk, not treatment benefit from any specific therapy.
Key terms
- MuLBSTA
- Weighted viral-pneumonia mortality score from this study.
- CURB-65
- Common pneumonia severity score used as comparator.
- AUROC
- Area under ROC curve for discrimination.
- Bacterial coinfection
- Scored MuLBSTA predictor of death.
- Multilobular infiltrates
- Radiographic pattern worth 5 MuLBSTA points.
- 90-day mortality
- Primary risk window for the score.
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Sample size:
Common questions
Cohort n?
528 viral pneumonia patients.
90-day deaths?
76 (14.4%).
MuLBSTA cut-off?
12 points.
AUROC vs CURB-65?
0.773 vs 0.717.
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