Skip to content
PaperFren

Does the plant clock gate auxin responses?

Open paper intelligence

The Arabidopsis circadian clock regulates auxin-responsive transcription and gates growth responses to auxin.

Source

The circadian clock regulates auxin signaling and responses in Arabidopsis

Covington MF, Harmer SL · PLoS biology · 2007

doi.org/10.1371/journal.pbio.0050222Read the full paper ↗282 citationscc by

Study at a glance

Design
Animal / in-vitro — Circadian transcriptomes overlapped with auxin responses; timed auxin transcriptional/growth assays
N
Arabidopsis seedling genome-wide profiling — no single organismal N in stored text
Population
Arabidopsis thaliana seedlings
Outcome
Clock gating of auxin transcriptional responses and growth

Structured fields used in claim comparison tables when every cited study has a complete layer.

What they did

Profiled circadian transcriptomes and tested overlaps with auxin-regulated genes, then assayed transcriptional and growth responses to auxin across the day.

What they found

>10% of seedling genes cycle; auxin-induced genes are enriched for clock regulation; endogenous/exogenous auxin transcriptional responses and auxin-driven growth are clock-gated.

The limits

What it doesn't show

Does not fully map every clock–auxin molecular node in all tissues or prove clinical relevance outside plants.

Key terms

Circadian clock
Endogenous ~24 h timing system coordinating physiology.
Auxin
Plant hormone controlling growth and development.
Gating
Time-of-day restriction of response amplitude to a stimulus.
Transcriptional profiling
Genome-wide measurement of mRNA abundance over time.

Flashcards

1 / 11

Research intelligence for this paper

See its role on concept claims, tensions it is part of, placement history, and related discoveries.

Open paper intelligence

Quiz yourself

1 / 6

Clock effect on auxin transcription:

Common questions

Are auxin genes clock-enriched?

Yes—more than expected by chance.

Is growth gated?

Yes—responses to exogenous auxin are clock-gated.

How many genes cycle?

Over 10% of expressed seedling genes in their estimate.

Organism?

Arabidopsis.

More on Circadian biology