Does light control fungal cellulase genes?
Neurospora photoreceptors WC-1, WC-2 and VVD influence cellulase expression; light-modulated cellulase regulation is conserved in filamentous fungi.
Source
Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa
Study at a glance
- Design
- Animal / in-vitro — Cellulase transcription profiling in photoreceptor mutants under light regimes
- N
- Fungal photoreceptor mutant expression study — no single sample N in stored text
- Population
- Fungi with WC-1/WC-2/VVD photoreceptor pathways
- Outcome
- Light modulation of cellulase gene expression via photoreceptors
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What they did
Profiled cellulase-related transcription in photoreceptor mutants and compared light effects on cellulolytic enzyme expression.
What they found
WC-1, WC-2 and VVD affect cellulase gene expression; light modulation of cellulases appears conserved, likely advantageous in nature.
The limits
What it doesn't show
Does not engineer industrial cellulase strains for bioreactors.
Key terms
- WC-1/WC-2
- White Collar photoreceptor/transcription-factor complex.
- VVD
- Vivid photoreceptor modulating light responses.
- Cellulase
- Enzyme degrading cellulose.
- Neurospora crassa
- Model filamentous fungus for light/circadian biology.
Flashcards
Research intelligence for this paper
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Quiz yourself
Photoreceptors affecting cellulase
Common questions
Which photoreceptors matter?
WC-1, WC-2, and VVD.
Is light modulation unique to Neurospora?
Authors argue it is conserved.
Why care?
Links light sensing to extracellular metabolism.
Model?
Neurospora crassa.
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